Life-sciences

  Polymerase Chain Reaction (PCR): Unveiling the Blueprint of Precision DNA Amplification In the world of molecular biology, few techniques have had as profound an impact as the Polymerase Chain Reaction (PCR). This revolutionary process, developed in the mid-1980s by Kary B. Mullis, has transformed the field of genetics, medicine, forensic science, and countless other disciplines. By allowing scientists to amplify specific DNA sequences with incredible precision, PCR has unlocked new frontiers in research, diagnostics, and technology development. Understanding PCR: The Molecular Copy Machine At its core, PCR is a molecular copy machine that enables the rapid amplification of a specific segment of DNA. It achieves this through a repetitive cycling process that generates millions to billions of copies of the target DNA sequence. The beauty of PCR lies in its simplicity and versatility, making it a cornerstone technique in modern molecular biology laboratories. The Components of PCR ...

 Antimicrobial Resistance  Antimicrobial Resistance is the ability of a microbe to resist antibiotics designed to kill or prevent the growth of the microbe. AMR is a global problem, affecting millions of people worldwide. In the United States, AMR is a serious health concern affecting around 3 million people.  Microbes attain antimicrobial resistance due to the over-dosage of antibiotics resulting in resistance to pathogens. A more important cause of antimicrobial resistance is the genetic change in the microbe's genome, which may cause antimicrobial resistance. Due to the advent of multidrug-resistant bacteria, infectious diseases are being more prevalent affecting the health system severely worldwide.  What are Superbugs Superbugs are micro-organisms resistant to a variety of antibiotics. If we are faced with the emergence of such a kind of superbug, it would be a challenge for us to control the spread of the pathogen.  How can we prevent AMR We can...